1- choose a great font (e.g., something that can still be clearly read when sized at 15 pt)
2- pick out a colour palette
3- find a few simple words and/or sayings
Font Guideline Tips
Remember, if you're mix and matching your fonts; opposites attract. Like serif & sans serif, fat & skinny and uppercase & lowercase. An example of great font combinations are Lora & Source Sans Pro and Futura & Georgia Italic.
The below project was created with some of this month's Sugarland goodies and a few basic printables that I designed in Photoshop, especially for this layout.